NUPLAZID® (pimavanserin) logo - once daily - 34 mg capsules

How people with Parkinson's disease describe hallucinations and/or delusions

Seeing things that aren't real

Such as people, either living or deceased, animals, or objects

Hearing things that aren't real

Such as hearing sounds, music, or voices

Paranoia

Such as believing people are talking about you or trying to access your money

False beliefs

Such as fears of your loved ones stealing from you, loved ones putting you in harm's way or being unfaithful

Don’t wait to talk to your healthcare provider

It's common for people living with hallucinations and/or delusions related to Parkinson’s disease to remain silent about these symptoms and not report them to a healthcare provider. By having an open discussion with your healthcare provider, he or she can help you identify and monitor these symptoms as your Parkinson’s disease progresses, and offer ways to treat your hallucinations and/or delusions. See how this Symptom Discussion Guide may help you have that conversation.

Reasons to talk to your healthcare provider at the first sign of Parkinson’s-related hallucinations and delusions include:

Calendar icon represents PD-related hallucinations and delusions over time and how NUPLAZID® treats PD-related hallucinations and delusions over time

They may get worse
over time

Parkinson’s-related hallucinations and/or delusions may get worse over time, and people who experience these symptoms may not have the ability to identify whether or not what they’re experiencing is real.
Orange circle outline with image of a house inside against white background

They can affect life
at home

Hallucinations and/or delusions associated with Parkinson’s disease can lead to increased caregiver distress, greater responsibility for caregivers, and even nursing home placement.
Actor portrayal of a couple with PD-related hallucinations and delusions talking to their doctor
"The biggest barrier to diagnosis is education. Patients and caregivers need to be aware that Parkinson’s-related hallucinations and delusions are indeed related to their Parkinson’s disease."

— Laxman Bahroo, MD Dr. Laxman Bahroo is a paid consultant for Acadia Pharmaceuticals Inc.

Ready to talk about treatment options?

It can be hard to know what questions to ask when talking to a doctor about treatment options. To help make this conversation less confusing, you or your loved one can download this simple guide and bring it to your next appointment to start the discussion with confidence.

Start The Conversation
Icon of a gold magnifying glass Find a specialist near you

Want to learn more about Parkinson’s-related hallucinations and delusions?

Get The Fact sheet
Back to top
Home Personal stories
IMPORTANT SAFETY INFORMATION and INDICATION
What is the most important information I should know about NUPLAZID?

  • Medicines like NUPLAZID can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia).

  • NUPLAZID is not approved for the treatment of patients with dementia who experience psychosis unless their hallucinations and delusions are related to Parkinson’s disease.

Who should not take NUPLAZID?

  • Do not take NUPLAZID if you have had an allergic reaction to any of the ingredients in NUPLAZID. Allergic reactions have included rash, hives, swelling of the tongue, mouth, lips, or face, throat tightness, and shortness of breath.
  • Do not take NUPLAZID if you have certain heart conditions that change your heart rhythm. It is important to talk to your healthcare provider about this possible side effect. Call your healthcare provider if you feel a change in your heartbeat.

What other warnings should I know about NUPLAZID?

  • QT Interval Prolongation: NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to prolong the QT interval. Tell your healthcare provider about all the medicines you take or have recently taken.

    Please also see What is the most important information I should know about NUPLAZID?

What medicine might interact with NUPLAZID?

  • Tell your healthcare provider about all the medicines you take. Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first.

What are the common side effects of NUPLAZID?

  • The common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088. You can also call Acadia Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).

Indication

NUPLAZID is a prescription medicine used to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

How should I take NUPLAZID?

The recommended dose of NUPLAZID is one 34 mg capsule once per day, taken by mouth, with or without food.

NUPLAZID is available as 34 mg capsules and 10 mg tablets.

Please read the full Prescribing Information, including Boxed WARNING.