NUPLAZID® is an FDA-approved treatment for hallucinations and delusions associated with Parkinson's disease psychosis.

Support for managing
disease–related hallucinations
and delusions 

Connect with a Care Coordinator for medication support

Actor portrayal of smiling woman, an Acadia Connect® Care Coordinator

Committed organizations

These organizations can provide you with more information about the nonmotor symptoms associated with PD.

Logo for The Parkinson’s Foundation

The Parkinson’s Foundation makes life better for people with Parkinson's disease by improving care and advancing research toward a cure. In everything we do, we build on the energy, experience, and passion of our global Parkinson’s community.

Phone: (800) 473-4636
Logo for The American Parkinson Disease Association (APDA)

The American Parkinson Disease Association (APDA) is the largest grassroots network dedicated to fighting PD and works tirelessly to assist those with PD live life to the fullest in the face of this chronic, neurological disorder. APDA provides support nationally through its network of Chapters and Information & Referral (I&R) Centers, as well as a national Research Program and Centers for Advanced Research.

Phone: (800) 223-2732
Logo for The Michael J. Fox Foundation for Parkinson's Research

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson’s and to ensuring the development of improved therapies for those living with the disease today through an aggressively funded research agenda.

Phone: (800) 708-7644
Logo for The Davis Phinney Foundation for Parkinson's

The Davis Phinney Foundation provides resources and connections that enable people living with Parkinson's to take action that can immediately improve their quality of life. The organization impacts hundreds of thousands of individuals and families each year through community programs, the funding of quality of life research, and extensive online content.

Phone: (866) 358-0285
Logo for Parkinson & Movement Disorder Alliance (PMD Alliance)

Parkinson & Movement Disorder Alliance (PMD Alliance) is a community of movers and motivators working hand-in-hand with those living with a diagnosis, their care partners, adult children, and support group leaders to deliver education and connection to those impacted by movement disorders.

Phone: (800) 256-0966
Brain icon representing changes associated with PD-related hallucinations and delusions

PD-related hallucinations and delusions may be more common than you think

Icon of a capsule representing NUPLAZID® clinical study and dosing information

See how NUPLAZID can help with PD-related hallucinations and delusions


What is the most important information I should know about NUPLAZID?

  • Medicines like NUPLAZID can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia).

  • NUPLAZID is not approved for the treatment of patients with dementia who experience psychosis unless their hallucinations and delusions are related to Parkinson’s disease.

Who should not take NUPLAZID?

  • Do not take NUPLAZID if you have had an allergic reaction to any of the ingredients in NUPLAZID. Allergic reactions have included rash, hives, swelling of the tongue, mouth, lips, or face, throat tightness, and shortness of breath.
  • Do not take NUPLAZID if you have certain heart conditions that change your heart rhythm. It is important to talk to your healthcare provider about this possible side effect. Call your healthcare provider if you feel a change in your heartbeat.

What other warnings should I know about NUPLAZID?

  • QT Interval Prolongation: NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to prolong the QT interval. Tell your healthcare provider about all the medicines you take or have recently taken.

    Please also see What is the most important information I should know about NUPLAZID?

What medicine might interact with NUPLAZID?

  • Tell your healthcare provider about all the medicines you take. Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first.

What are the common side effects of NUPLAZID?

  • The common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1‑800‑FDA‑1088. You can also call Acadia Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).


NUPLAZID is a prescription medicine used to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

How should I take NUPLAZID?

The recommended dose of NUPLAZID is one 34 mg capsule once per day, taken by mouth, with or without food.

NUPLAZID is available as 34 mg capsules and 10 mg tablets.

Please read the full Prescribing Information, including Boxed WARNING.