NUPLAZID is an FDA-approved treatment for hallucinations and delusions associated with Parkinson's disease psychosis.
Ask your healthcare provider about treatment
If you or your loved one is seeing, hearing, or experiencing things that others don't (hallucinations) or believing things that aren't true (delusions), NUPLAZID may help.
NUPLAZID is the only medicine approved to treat hallucinations and delusions associated with Parkinson's disease (PD).
Parkinson’s disease–related hallucinations and delusions may be more common than you think
Around 50% of people living with Parkinson’s disease (PD) may experience hallucinations and/or delusions over the course of their disease, and these symptoms can get worse over time.
Whether these symptoms occur sometimes or have become more frequent, it’s important to share your experiences with your healthcare provider. The sooner your doctor knows about new or worsening symptoms, the sooner they can help.
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Learn more about NUPLAZID and PD-related hallucinations and delusions, including what to look for and how to get help.
IMPORTANT SAFETY INFORMATION and INDICATION
What is the most important information I should know about NUPLAZID?
Medicines like NUPLAZID can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia).
NUPLAZID is not approved for the treatment of patients with dementia-related psychosis unrelated to the hallucinations and delusions associated with Parkinson’s disease psychosis.
Who should not take NUPLAZID?
- Do not take NUPLAZID if you have had an allergic reaction to any of the ingredients in NUPLAZID. Allergic reactions have included rash, hives, swelling of the tongue, mouth, lips, or face, throat tightness, and shortness of breath.
- Do not take NUPLAZID if you have certain heart conditions that change your heart rhythm. It is important to talk to your healthcare provider about this possible side effect. Call your healthcare provider if you feel a change in your heartbeat.
What other warnings should I know about NUPLAZID?
- QT Interval Prolongation: NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to prolong the QT interval. Tell your healthcare provider about all the medicines you take or have recently taken.
Please also see What is the most important information I should know about NUPLAZID?
What medicine might interact with NUPLAZID?
- Tell your healthcare provider about all the medicines you take. Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first.
What are the most common side effects of NUPLAZID?
- The common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088. You can also call Acadia Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).
NUPLAZID is a prescription medicine used to treat hallucinations and delusions associated with Parkinson’s disease psychosis.
How should I take NUPLAZID?
The recommended dose of NUPLAZID is one 34 mg capsule once per day, taken by mouth.
NUPLAZID is available as 34 mg capsules and 10 mg tablets.
Please read the full Prescribing Information, including Boxed WARNING.